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Ciprofloxacin vs azithromycin which is better

Bacteria is less resistant to this antibiotic, meaning that Zithromax (azithromycin) will fight off the bacteria better. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection. Immediate release form can be taken with or without food. Cipro (ciprofloxacin) is available in generic Ciprofloxacin vs Azithromycin for Gonorrhea. Azithromycin is at least as effective and well tolerated as ciprofloxacin in the treatment of gonococcal infections 4. Results of single-blind comparative study of azithromycin and ciprofloxacin for gonorrhea 4. • Ciprofloxacin inhibits bacterial DNA synthesis In conclusion, 1 g azithromycin is at least as clinically and microbiologically effective and well tolerated as 500 mg of ciprofloxacin in the treatment of gonococcal infections. The drug is particularly useful for sailors and people constantly on the move 1. The safety in everyday clinical usage of three 4-quinolone antibiotics, (ciprofloxacin, norfloxacin and ofloxacin), was compared with similar data for azithromycin and cefixime, each agent being examined by Prescription-Event Monitoring (PEM) during the early post-marketing period. 2. In PEM the Common cold is a self resolving viral disease.Antibiotics are not indicated. Just take plenty of oral fluids,nasal drop as and when needed for blocked nose, paracetamol for headache and fever. Don't take antibiotics

Azithromycin Side Effects - Warnings Side Effects and Mor

  1. Zithromax Z-PAK ( azithromycin) and Cipro ( ciprofloxacin) are antibiotics used to treat susceptible bacterial infections. Zithromax and Cipro belong to different antibiotic classes. Zithromax is a macrolide antibiotic and Cipro is a quinolone antibiotic
  2. The regimen was 500 mg azithromycin for three days/week for three weeks vs. ciprofloxacin, 500 mg bid for 20 days. Evaluation at 4-6 weeks showed more clinical cures (31/45 vs. 15/44) and more microbial eradication (36/45 vs. 17/44) favoring azithromycin. Both results are highly significant by statistical analysis
  3. Streptococci (pneumoniae/ pyogenes/ viridans group) Enterococci (Group D strep) Staph epidermidis (coagulase negative) Staph aureus (Methicillin sensitive
  4. These antibiotics are better than the worst when it comes to C. diff, but aren't as good as the winners. Azithromycin (Zithromax, Z-Pak) Azithromycin (Zithromax, Z-pak) has many uses including sinusitis, strep throat, chlamydia, H. pylori stomach infections, among others. It's the jack-of-all-trades antibiotic, and very few bacteria are.
  5. Better judgment prevailed and 2 days later I got tested and told today I have NGU. I was given 4 250mg pills of azithromycin to take today and then told to follow up with Ciprofloxacin (500mg tabs twice daily) for 7 days. The concern is that 5 days after getting the unprotected oral from the pro, I got the same from my wife (we haven't had.
  6. Azithromycin at a dose of 500mg daily is an effective treatment for fully sensitive strains of S. Typhi but is associated with delayed treatment response and prolonged bacteraemia when compared with ciprofloxacin within the context of a human challenge model
  7. Dr. Michael Ein answered 48 years experience Infectious Disease Cipro (ciprofloxacin): Cipro (ciprofloxacin) would have a better chance of curing a UTI than would Azithromycin which is less active against gram negative enteric bacteria a..

Brief Answer: depends Detailed Answer: Hi and welcome. For bacterial bronchitis it is better to use Ciprofloxacin which is more effective and there is less resistency. Also Amoxicilin or Claritromicin may be used. If you have COPD or Pneumonia then Azytromicin should be added. Also, many bronchitis are viral so antibiotic may not work at all Cipro (ciprofloxacin) is a good, cheap antibiotic that treats many types of bacterial infections, but it interacts with some food and drugs. Prevents and treats infections. Ery-Tab (Erythromycin) works well to treat a variety of bacterial infections, but check for drug interactions before taking it. Cipro (ciprofloxacin) is available in generic Overall, azithromycin was as effective as ciprofloxacin in decreasing the duration of illness (36.9 hours vs. 38.2 hours, respectively) and the number of stools (6.4 vs. 7.8, respectively) Dr. Michael Ein answered Infectious Disease 48 years experience Cipro (ciprofloxacin): Cipro (ciprofloxacin) would have a better chance of curing a UTI than would Azithromycin which is less active against gram negative enteric bacteria and does not achieve high levels in the urine. 4.9k views Reviewed >2 years ag These azithromycin results compare favorably with those of No. of patients or mean 6 SD other antimicrobial agents tested recently for typhoid fever, Parameter including ceftriaxone, cefixime, and fluoroquinolones (16, 20), Azithromycin Ciprofloxacin and confirm the earlier finding that azithromycin is effective No. of patients treated 36 28.

Comparing Amoxicillin vs Ciprofloxacin. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Amoxicillin Remove Amoxicillin from your drug comparison. Ciprofloxacin Remove Ciprofloxacin from your drug comparison. Add another drug to compare Ciprofloxacin has better activity against Gram-negative bacilli. Ofloxacin has a longer half-life and higher serum levels. Ofloxacin does not significantly alter theophylline concentrations. Urinary tract infections. Ciprofloxacin and ofloxacin are equally effective in women with complicated lower urinary tract infection 11 Comparing Ciprofloxacin vs Clindamycin. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Ciprofloxacin Remove Ciprofloxacin from your drug comparison. Clindamycin Remove Clindamycin from your drug comparison. Add another drug to compare Cipro (ciprofloxacin) and Levaquin (levofloxacin) are fluoroquinolone antibiotics used for the treatment of bacterial infections. Cipro and Levaquin stop the multiplication of bacteria by preventing the reproduction and repair of their DNA. Even though Cipro and Levaquin belong to the same drug class there are differences between their side effects, dosage, types of infections treated, and.

Cipro may cause serious side effects, including:. diarrhea; dizziness; drowsiness; headache; stomach upset; abdominal pain; nausea/vomiting; blurred vision; nervousness; anxiety; agitation; sleep problems (insomnia or nightmares), and ; rash; Tell your doctor if you experience serious side effects of Cipro including severe dizziness, fainting, fast or pounding heartbeats; sudden pain, snapping. Differences Between Azithromycin and Clarithromycin Azithromycin vs Clarithromycin Definitely, antibiotics are one of the most essential medicines. Antibiotics are used to fight infections. The common signs and symptoms of infection are: fever, redness around the affected area, and even pain. To eliminate all these troublesome signs and symptoms of infection, taking antibiotics is a necessity

Azithromycin/QT Prolonging Agents Interactions . This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing. Levofloxacin is not recommended in pregnancy, but azithromycin alone is likely to be effective. Since you have already treated yourself and your symptoms are improving, perhaps nothing more need be done. But you should not assume an STD was the cause of the problem. Read More. Levofloxacin hydrate 100 Mg 3Xdaily

To calculate the steady-state concentrations of azithromycin in human tonsils, pharmacokinetic data from a 500 mg single dose study 2 and a study that used two 250 mg doses administered 12 hourly 8 were combined. The first study measured azithromycin concentrations in homogenized tonsils from 1 to 12 h post-dose, whereas the second study used data obtained between 13 and 178 h, without. We report that azithromycin (AZM) and ciprofloxacin (CIP) combination is synergistic in vitro both against planktonic and biofilm cells of Pseudomonas aeruginosa.. Confocal laser scanning microscopy revealed that in the presence of AZM + CIP combination, mainly dead cells were seen within the biofilm after 24 h.. This is the first report which cites that in vivo oral therapy with AZM + CIP. oral ingestion is just as effective as IV for treatment) IV medication = medication given intravenously. - medication takes effect immediately after the infusion. - administers a bolus of the medication quickly (within 5 minutes) - requires an IV line. - bypass first pass metabolism in the liver

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The research examines the cellular and immune mechanisms of two FDA-approved antibiotics, azithromycin (AZT) and ciprofloxacin (CPX) in the treatment of cystic fibrosis (CF). The research confirmed the drugs' effect in regulating abnormal organelle pH and enhanced innate immunity activity in different CF epithelium models, and draw. Significantly higher eradication (36/45:17/44) and significantly higher clinical cure (31/45:15/44) were achieved in the group of patients treated with azithromycin compared with the the ciprofloxacin group. In patients with prostatitis caused by C. trachomatis, the drug of choice is azithromycin Azithromycin (Zithromax) 1 g orally in a single dose. $ 20.50 (brand) Ceftriaxone (Rocephin) 250 mg IM in a single dose. 13.00 (brand) Ciprofloxacin (Cipro) 500 mg orally twice daily for 3 days. To evaluate the efficacy of azithromycin for treatment of shigellosis, 75 children with dysenteric diarrhea in whom Shigella was isolated were randomized to receive either azithromycin or cefixime orally for 5 days. Treatment with azithromycin led to a significantly higher bacteriologic eradication rate (P < 0.01) and a trend toward better clinical efficacy (P = 0.1) than with cefixime therapy azithromycin also was found to be as effective and better tolerated than a combination therapy of eryth-romycin and a cephalosporin in hospitalized patients, again excluding ICU patients.27 These data do not provide an adequate basis for the use of mono-therapy with either agent among patients sick enough to be admitted to the ICU. However, thei

Compare Azithromycin vs Cipro - Iodine

Azithromycin Oral bioavailability of azithromycin is 37% (food decreases absorption). Excretion in the bile, only 6% excreted unchanged in urine. Protein binding: 50%; Vd: 30 L/kg; Penetration: Concentrates intracellularly within tissues, with a long half-life (2-4 days). Penetrates most tissues, but not urine or meninges. Clarithromyci The aim of this study was to compare the in vitro susceptibility of Klebsiella pneumoniae, Pseudomonas aeruginosa and Stenotrophomonas maltophilia to three fluoroquinolones. The minimum inhibitory concentrations (MICs) to ciprofloxacin, levofloxacin and moxifloxacin were examined by E-test® for a total of 40 K. pneumoniae strains, 40 S. maltophilia strains and 40 P. aeruginosa strains

Since azithromycin has a particularly prolonged intracellular half-life, both in systemic and topical form, it is dosed less frequently than other ophthalmic drugs. For AzaSite, the standard dosage is one drop every eight to 12 hours for the first two days, then one drop daily for five more days Ciprofloxacin is resistant so levofloxacin should not be used Tigecycline has poor urine penetration and is IV Nitrofurantoin Rule #4: Microbiology always has more information that what is reported Fosfomycincan also be tested but is expensive. Ear infections are caused by either a bacteria or a virus, and most kids get them before they turn two years old. Ear infections, which often occur after a cold or throat infection, can be unpleasant or downright painful

Azithromycin, sold under the brand names of Zithromax and Zmax, is used to treat bacterial infections, such as epididymitis. Azithromycin side effects can include intestinal symptoms, such as nausea, vomiting, stomach pain and diarrhea, or a mild skin rash may appear. Notify your doctor if these side effects do not go away or become severe Ciprofloxacin extended-release (long-acting) tablets are used to treat kidney and urinary tract infections; however, some types of urinary tract infections should only be treated with ciprofloxacin extended release tablets if no other treatment options are available. Ciprofloxacin is in a class of antibiotics called fluoroquinolones 4. Aztreonam - high rates of resistance at most institutions, so use only if PCN-allergic, and empirically double-cover. 5. Fluoroquinolones - Ciprofloxacin (~70% coverage) > Levofloxacin (~65%), NOT Moxifloxacin (0%) - usually used as double coverage, not for monotherapy for empiric Pseudomonas treatment. 6 Bacterial strains and antibiotics. The bacterial strain used was Escherichia coli ATCC 25922. Ciprofloxacin (Sigma-Aldrich, St Louis, MO, USA) stock solutions were prepared at 1 mg ml −1 in 0.1. Macrolides like azithromycin are the current drugs of choice when antibiotic treatment is indicated. Resistance to macrolides in Campylobacter has remained stable. In 2017, 28% of C. jejuni and 38% of C. coli isolates were resistant to ciprofloxacin, and 3% of C. jejuni and 7% of C. coli isolates were resistant to the macrolide azithromycin

Ciprofloxacin (Cipro) vs Azithromycin (Zithromax

Severe Interactions. These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. STRONG AND MODERATE CYP3A4. Bactericidal vs Bacteriostatic—When to Apply. From the above comparison, it seems that bactericidal antibiotics are the better choice, which is believed for a long time being as a misconception. The type of infection you have will determine which type of antibiotic to use. Bactericidal drugs treat diseases like meningitis and endocarditis

Ciprofloxacin (Cipro) received an overall rating of 4 out of 10 stars from 215 reviews. See what others have said about Ciprofloxacin (Cipro), including the effectiveness, ease of use and side effects 1 The safety in everyday clinical usage of three 4-quinolone antibiotics, (ciprofloxacin, norfloxacin and ofloxacin), was compared with similar data for azithromycin and cefixime, each agent being examined by Prescription-Event Monitoring (PEM) during the early post-marketing period.. 2 In PEM the exposure data are derived from general practitioner prescriptions confidentially provided by the.

Comparative trial of azithromycin and ciprofloxacin in the

  1. Secondly, combination of ciprofloxacin and azithromycin was chosen as the selective stress for the following cultivation; it is able to penetrate the biofilms and kill the bacterial cells inside.
  2. Employing cystic fibrosis respiratory epithelial cells, here we show that drugs AZT and ciprofloxacin (CPX) act as acidotropic lipophilic weak bases and confer in vitro effects on intracellular organelles similar to the effects of CQ. Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells. Jens F.
  3. Difference Between Erythromycin and Clarithromycin Erythromycin vs Clarithromycin Antibiotics are very powerful and potent drugs. If penicillin was not invented, many people would have probably died due to infection. Drugs do wonderful things for us. If abused, they can also bring harm to our body systems. One of the most common antibiotics being prescribed and given by our physicians are [

Cipro vs. Macrobid. Cipro and Macrobid (nitrofurantoin) are both antibiotic drugs, but they belong to different drug classes. Cipro is a fluoroquinolone antibiotic. Macrobid is a nitrofuran. MAIN RESULTS. More patients in the azithromycin group had clinical and bacteriological success than in the ciprofloxacin group (table). Patients in the azithromycin group had a shorter duration of diarrhoea (median 30 v 78 h, p<0.001), a lower volume of stools, and a lower frequency of vomiting (median 0 v 4 episodes/patient, p<0.001); they required less fluids and excreted V cholerae for a. Azithromycin 500 mg once daily X 3 days. Gastroenteritis: severe diarrhea. Common pathogens. Ciprofloxacin 500mg po bid OR Levofloxacin 500mg po qd x 3 to 5 days. OR. Bactrim DS po q12h. Pathogen Specific. Clostridium difficile: Metronidazole 500mg po tid x 10-14 days or Vancomycin 125mg po qid x 10-14 days Ciprofloxacin is a commonly utilized antibiotic; however, due to its bacteria-specific effectiveness, ciprofloxacin for prostatitis may range from nominally to extremely successful. Taking ciprofloxacin may cause some patients to experience sensitivity to light. Ciprofloxacin belongs to a class of antibiotics known as fluoroquinolones

A comparison of ciprofloxacin, norfloxacin, ofloxacin

Which is better anit biotic azithromycin or ciprofloxacin

It is best to take these medicines at least 2 hours before or 4 to 6 hours after taking ciprofloxacin. These medicines may keep ciprofloxacin from working properly. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. Dosin Clarithromycin vs. Azithromycin for Pneumonia. Am Fam Physician. 2004 Jan 15;69 (2):420. Most guidelines on the management of community-acquired pneumonia advocate adding a macrolide antibiotic to.

Ciprofloxacin for chlamydia has not yet been approved as a treatment modality as of 2011; however, a number of other antibiotic options exist. Among these are azithromycin and doxycycline as well as tetracycline and erythromycin. It is likely that ciprofloxacin for chlamydia will take a significant amount of time to be regularly utilized. Iv rocephin followed by. This article is as effective against a. His first run back was. Purpose azithromycin vs azithromycin is better for easy-to-remember names levaquin. More effective against a study conducted to prevent genox nolvadex As such guidelines direct the outpatient treatment of azithromycin over monotherapy with a. Compare head. Ciprofloxacin 500 MG Tablet is a broad-spectrum fluoroquinolone antibiotic used for the treatment of bacterial infections that affect the skin, joints, lungs, or urinary tract. It is effective against a large number of bacteria. It kills or prevents the growth of bacteria in the body. It is not effective against infections caused by viruses. Common side effects of Ciprofloxacin 500 MG Tablet. Poschet J, Perkett E, Timmins G, Deretic V. Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells. bioRxiv. 2020. Coutard B, Valle C, de Lamballerie X, Canard B, Seidah NG, Decroly E. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade Bottom Line - Clindamycin vs Amoxicillin Clindamycin is a lincosamide antibiotic which has been approved by the US FDA for the treatment of streptococcal, anaerobic, and staphylococcal infections. It is available as phosphate for intravenous or intramuscular injection, as clindamycin hydrochloride for oral administration in capsules, and as.

Ciprodex. It is a combination product which contains two drugs - dexamethasone and ciprofloxacin. Dexamethasone is a steroid that reduces the actions of chemicals in the human body which cause inflammation. Ciprofloxacin is an antibiotic which treats infections caused by pathogenic bacteria. It belongs to a group of medications called. Here we'll guide you to the very best prices available today. Ciprofloxacin Cipro 500 Mg Tablet - A month's worth of pills is available from wholesalers for less than $20. ciprofloxacin cipro 500 mg tablet Best Quality and EXTRA LOW PRICES, ciprofloxacin mg tablet 500 cipr Cipro Vs Cephalexin For Uti - A month's worth of pills is available from wholesalers for less than $20. cipro vs cephalexin for uti Best Quality and EXTRA LOW PRICES, uti vs for cephalexin cipro. View this post on Instagram For example, 2 fewer failures in the azithromycin group (3 of 155 in the azithromycin group vs. 0 of 155 in the doxycycline group) would give an upper boundary of the 90% confidence interval of 4. Utine CA. Update and critical appraisal of the use of topical azithromycin ophthalmic 1% (AzaSite) solution in the treatment of ocular infections. Clin Ophthalmol. 2011;5:801-9. [PMID:21750614] Comment: A review of the use of topical azithromycin in the treatment of ocular infections including conjunctivitis. Summarizes the available RCTs

Zithromax vs. Cipro - RxLis

Azithromycin (1 g stat or 500 mg, once daily, for three days) can be used instead of ciprofloxacin as a second-line treatment for severe traveller's diarrhoea, when antibiotics are required. Azithromycin is recommended for pregnant women (ciprofloxacin is contraindicated) or in areas where there is quinolone resistance, e.g. South East Asia Shigella infections treated with ciprofloxacin or azithromycin: CDC recommendations updated . by Press Release . June 10, 2018. Drugs and antibiotics, US News. No Comments. In.

Comparative Analysis of Azithromycin and Ciprofloxacin in

Safety Announcement [3-12-2013] The U.S. Food and Drug Administration (FDA) is warning the public that azithromycin (Zithromax or Zmax) can cause abnormal changes in the electrical activity of the. In reviewing these patients, those receiving azithromycin were about twice as likely (8.5% vs 4.3%, respectively) to report diarrhea or loose stools, while those receiving levofloxacin reported nausea six times more often (6% vs 0.8%, respectively) I am allergic to Aleve and naprosyn, Cipro also. I break out with hives. Can I take Pepto Bismal for travelers diarrhea ?. Ciprofloxacin IV 400 mg Q12H + Metronidazole IV 500 mg Q8H Note: e.coli resistance is >20% to ciprofloxacin, therefore, ciprofloxacin is only recommended for life-threatening beta-lactam allergic patients Diverticulitis Acute, Uncomplicated Consider deferral of antibiotic9 Complicated Ceftriaxone IV 1g Q24H + Metronidazole IV 500 mg Q8

  1. istration (FDA) made a statement declaring they were aware of the cardiovascular deaths associated with azithromycin, in comparison to persons treated with amoxicillin, ciprofloxacin or no drug
  2. istered, azithromycin may be less or totally ineffective
  3. The Panel recommends against the use of chloroquine or hydroxychloroquine and/or azithromycin for the treatment of COVID-19 in nonhospitalized patients (AIIa). Adverse Effects. Chloroquine and hydroxychloroquine have similar toxicity profiles, although hydroxychloroquine is better tolerated and has a lower incidence of toxicity than chloroquine
  4. istration of azithromycin for up to a year
  5. istration and ensure better patient compliance, as compared to tetracycline and erythromycin, which must be taken several times a day for three days. Cost is another consideration for governments and health facilities

Video: Which Antibiotics Are Less Likely to Cause Diarrhea From C

azithromycin and ciprofloxacin together - MedHel

For non-pregnant patients, doxycycline is preferred over azithromycin [ambulatory vs. inpatient setting not specified]. Professional society guidance regarding use of azithromycin to treat COVID-19 IDSA April 13 Because of the potential for toxicity, the panel recommends that the HCQ+AZ combination only be used in th Azithromycin. 27,28 This agent is a macrolide antibiotic with a decent spectrum of bacterial coverage. It has slightly better coverage for Haemophilus influenzae when compared with Augmentin, and its atypical bacterial coverage is better than its gram-positive coverage (97%) vs. ceftriaxone and doxycycline (95%); moxifloxacin (90%) vs. ofloxacin plus metronidazole (91%); doxycycline plus metronidazole (91%) or ciprofloxacin plus tinidazole (96%); azithromycin alone (97%) or azithromycin plus metronidazole (96%) vs. metronidazole plus doxycycline plus cefoxitin plus probeneci After an oral dosage of 500 mg o.d for 3 days, significant levels of azithromycin can be detected in most tissues for 7-10 days. It has been proposed that azithromycin penetrates fibroblasts and phagocytes in concentrations 100-200 times greater than that of extracellular compartment

ANTIBIOTICOS BETALACTAMICOS PDF

Treatment responses to Azithromycin and Ciprofloxacin in

Azithromycin increased the risk of diarrhea and abnormal pain, compared to placebo treatments and other macrolides. Overall, the study demonstrated azithromycin's superior capacity to decrease bronchiectasis exacerbations, and can eventually help physicians deciding which antibiotic to prescribe. This meta-analysis suggested that long-term. *Azithromycin is the preferred antibiotic for traveler's diarrhea. If antibiotic is needed, take 1 dose of Azithromycin 500mg. If diarrhea continues, take a 2nd dose about 12 hours later. Stop antibiotic when diarrhea resolves. If needed continue Azithromycin 500mg daily for up to 3 days. Ciproflloxacin may b

ATI pharm memory graphics at Augustana College (SDAntimicrobial Structures - Medicinal Chemistry 5220 with

Z pack vs cipro Answers from Doctors HealthTa

Ciprofloxacin and azithromycin are two recommended oral antibiotics. If your healthcare provider prescribes an antibiotic, take it exactly as directed and finish taking all the pills even if you feel better. More Information. Antibiotic Resistance and Shigella Infections Azithromycin - is the first line treatment. It is 100-fold more active against this organism than the tetracyclines or most fluoroquinolones. However, resistance is increasing. In certain regions, the estimated rate of azithromycin resistance in isolated M. genitalium strains has been as high as 40 percent. Suggested treatment dose is. Lancet 2012; 380 (9840): 484-90. Peterson J, Kaul S, Khashab M, Fisher AC, Kahn JB. A double-blind, randomized comparison of levofloxacin 750 mg once-daily for five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated urinary tract infections and acute pyelonephritis

The CDC treatment guidelines recommend dual therapy with two different antibiotics: ceftriaxone (a cephalosporin) and azithromycin (CDC, 2015). Each of these antibiotics has a different mechanism of action against N. gonorrhea (the bacteria that causes gonorrhea). This two-pronged approach increases the chances that the treatment will be effective New isn't always better. When several antibiotics have similar coverage, select the least expensive. Antibiotic Classes by Coverage: Gram positive coverage: 1. Penicillins (ampicillin, amoxicillin) penicillinase resistant (Dicloxacillin, Oxacillin) * 2. Cephalosporins (1st and 2nd generation)* 3. Macrolides (Erythromycin, Clarithromycin. Ciprofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics known to be resistant to ciprofloxacin. Azithromycin was included as a second-line therapy for adult patients; this was (most likely) not recommended for children in these guidelines due to limited evidence at that time in regards to its efficacy . Antimicrobial Treatment schedule for children Limitations 1 st Line: Ciprofloxacin 15mg/kg orall Azithromycin has rapidly been adopted as a repurposed drug for the treatment of COVID-19, despite the lack of high-quality evidence. In this review, we critically appraise the current pharmacological, preclinical and clinical data of azithromycin for treating COVID-19. Interest in azithromycin has been fuelled by favourable treatment outcomes in other viral pneumonias, a documented antiviral.