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Atypical endometriosis

Atypical endometriosis can be observed in contiguity with malignant epithelial tumors. It is considered that atypical endometriosis possesses a precancerous potential. Carcinoma may arise in residual foci of atypical endometriosis at the same or other sites Atypical endometriosis is related to a higher recurrence rate Recurrence rates for AE were higher than for TE. Although the AE group included no patient with malignant transformation in this study, considering the higher recurrence as well as the possibility of malignant transformation, long-term close surveillance is warranted

Objective: To investigate the clinicopathologic features of atypical endometriosis (AEM) and to discuss the relationship between AEM and tumors. Methods: A retrospective analysis was performed of 163 cases of AEM, which were retrieved from the Department of Pathology files at the Tianjin Central Obstetrics and Gynecology Hospital between Jan 2004 and Dec 2006 It has been suggested that atypical endometriosis is a precursor lesion of endometriosis-associated ovarian cancer (EAOC). The aim of this study is to evaluate if cytologic (cellular) atypia and architectural atypia (hyperplasia), histologic findings described as atypical endometriosis, play a different role in patients with EAOC To investigate the clinicopathologic features of atypical endometriosis (AEM), and to discuss the relations between AEMs and tumors. A retrospective analysis was performed on 163 cases of AEMs. The changes in the glandular epithelium, stroma, and their background and the relationship with coexisting tumors were observed. The AEMs account of for 4.4% (163/3,724) of the endometriosis (EM) cases Atypical endometriosis is rare and difficult to diagnose. The most common atypical locations are the gastrointestinal tract, urinary tract, lung, umbilicus, inguinal area, breast, and pelvic nerves, as well as abdominal surgical scars

ATYPICAL ENDOMETRIOSIS. Did you know that there are some forms of endometriosis that are classified as atypical and may be considered as precursor lesions (precancerous)? How common are atypical lesions and will all of them undergo malignant transformation if left untreated? Research is still limited, so we don't really know for sure Endometrial hyperplasia thickens the uterus lining, causing heavy or abnormal bleeding. Atypical endometrial hyperplasia raises the risk of endometrial cancer and uterine cancer. The condition tends to occur during or after menopause. Progestin therapy can ease symptoms Atypical endometriosis: this has been reported in 1.7 - 4.4% of endometriotic lesions and is considered the precursor lesion for endometriosis associated carcinomas (clear cell or endometrioid); may be in continuity with these tumor

The topics covered include the contentious issue of so-called atypical endometriosis, stromal endometriosis, polypoid endometriosis, and the association of endometriosis with florid mesothelial hyperplasia. The propensity of endometriosis to undergo neoplastic transformation (especially to endometrioid and clear cell carcinoma) is well known Atypical endometriosis was found in 18 clear cell carcinomas, in seven endometrioid carcinomas, in four serous carcinomas, in three mucinous borderline tumours, and in one serous borderline tumour. In 13 cases, the atypical endometriosis was in contiguity with malignant epithelial tumours

Atypical Ovarian Endometriosis : AJSP: Reviews & Report

The most common atypical locations are the gastrointestinal tract, urinary tract, lung, umbilicus, inguinal area, breast, and pelvic nerves, as well as abdominal surgical scars. Gastrointestinal lesions are the most common extragenital manifes There are different stages of endometrial hyperplasia : simple, complex, simplex atypical, and complex atypical. The atypical categories mean that abnormal cells are now present, which may (or may not) develop into cancerous cells. Simple (aka mild) hyperplasia carries the smallest risk of developing into cancer Atypical endometriosis is considered a premalignant lesion of the subtype of endometrioid and clear cell carcinoma. This owing to the coexistence of AE and ovarian cancer had been reported several times. However, the cases of AE that transformed to cancer are rarely reported [ 8, 28 ] Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis. Sáinz de la Cuesta R, Izquierdo M, Cañamero M, Granizo JJ, Manzarbeitia F Eur J Obstet Gynecol Reprod Biol 2004 Mar 15;113(1):87-93. doi: 10.1016/S0301-2115(03)00367-1 Atypical Endometrial Hyperplasia is a condition that occurs in the endometrium due to an abnormally increased growth of the endometrial glands. On examination of a biopsy specimen under a microscope, the pathologist may observe cell abnormalities (cytological atypia

While endometriosis usually affects tissues in the pelvic region, in rare cases, atypical endometriotic tissue can infiltrate and grow in distant sites in the abdomen and chest.. A review shows that while the condition can be difficult to diagnose, the cyclic nature of symptoms — waxing and waning along with the menstrual cycle — may indicate the presence of atypical endometriosis Thomas and Campbell classified atypical endometriosis on the basis of the following histologic criteria: large nucleus, hyperchromatic or pale, with accentuated pleomorphism, decrease in the cytoplasm/nucleus relation, and cellular stratification The AE group displayed a significantly higher cumulative recurrence rate than the TE group (p = 0.0057, log-rank test). No patients were diagnosed with atypical endometriosis to malignant transformation during the follow-up periods. However, two typical endometriosis patients experienced borderline malignancy and serous carcinoma, respectively

Atypical endometriosis has been proposed as a premalignant lesion strongly associated with endometriosis-associated ovarian cancer (EAOC) [4, 5]. Atypical endometriosis also refers to two different histologic findings: cellular atypia, also known as cytologic atypia, and architectural atypia, commonly referred to as hyperplasia Symptoms of atypical hyperplasia of the endometrium occur in the form of certain manifestations inherent in each specific character and type of development of the pathological process. So with the glandular form of the disease, which is inherently benign, proliferation of the stroma and endometriosis glands occurs Endometriosis creates endometrial cells that resemble the uterus lining, causing them to grow in atypical places in the body instead of inside of the uterus Atypical endometriosis chapter11. Hello, I was misdiagnosed via CT scan and MRI with stage 3C ovarian cancer when I went to the ER with pelvic pain due to a 11 x 10 cm mass on my ovary. The scans also showed enlarged lymph nodes and nodularity in my omentum. After surgery with a gyne-oncologist to remove the ovary and tube, it was discovered. Herein, a case of primary endometrioid adenocarcinoma of the vagina with a microglandular pattern arising from pre-existing endometriosis long after a hysterectomy Pathol Int . 2010 Sep;60(9):636-41. doi: 10.1111/j.1440-1827.2010.02573.x

Atypical endometriosis is related to a higher recurrence rat

We present a case of an incidental diagnosis of endometriosis in an asymptomatic, tamoxifen-exposed woman found to have atypical hyperplasia in her ovarian endometriosis and within the eutopic endometrium Atypical endometriosis is defined as epithelial lining of endometriosis with large hyperchromatic or pale pleomorphic nuclei, increased nucleocytoplasmic ratio, and cellular crowding, stratification, or tufting (3)

Detecting Endometrial Carcinoma with Ultrasound

[Atypical endometriosis: a clinicopathologic study of 163

The other case (Figs 3 through 6) arose in atypical endometriosis of the left ovary and was associated with synchronous atypical endometriosis of the right ovary. FIGURE 2. Case no. 3. Atypical endomeJriosis showing epithelial tufting, stratification, nuclear enlargement, and hyperchromatism The risk of malignant transformation of atypical endometriomas is about 4-fold increase. There are histological evidences of transition from endometriosis, through atypical endometriosis, to EAOC . The most important features in the endometrial epithelium for the study of malignant transformation are cytologic atypia and/or hyperplasia atypical endometriosis and the corre-sponding clinical manifestations. Discuss the role of imaging in evaluat-ing patients with atypical endometriosis. Identify imaging findings of atypical endometriosis in the abdominal wall, umbilicus, inguinal area and round liga-ments, small bowel, appendix, thoracic cavity, and pelvic nerves

Discussion. Atypical endometriosis implants are considered more biologically active than typical implants. The new ASRM classification introduces, as an adjunct to the revised AFS classification , the categorization of peritoneal and ovarian implants in three subgroups: red (including red, red-pink, and clear lesions), white (including white, yellow-brown, and peritoneal defects), and black. Gastrointestinal endometriosis is the most common extragenital location. The diaphragm is the most frequent extrapelvic site of endometriosis. Specialist imaging is fundamental to the evaluation of atypical sites endometriosis. Radiography, ultrasonography, thin-section computed tomography, or magnetic resonance imaging can be used 1. Hum Pathol. 1988 Sep;19(9):1080-4. Ovarian tumors associated with atypical endometriosis. LaGrenade A(1), Silverberg SG. Author information: (1)Department of Pathology, George Washington University Medical Center, Washington, DC 20037. We present five cases in which ovarian neoplasms (three clear cell carcinomas, two endometrioid carcinomas) were associated--and in four cases contiguous.

Prognostic importance of atypical endometriosis with

Endometriosis is defined as presence of endometrium including glands and stroma at locations other than the uterine cavity. Atypical endometriosis is rarely seen, accounting for 4.38% amongst endometriosis cases and is reported to possess a precancerous potential. We are reporting a case of primigravida with term gestation, taken up for emergency caesarean section in view of severe. Defenition Endometriosis: the presence of functional endometrium outside the uterine cavity. Atypical (Subtle) endometriosis: Endometriotic lesions that lack the typical black-blue, powder-burn appearance. (Jansen & Russel,1986) 4. Typical lesions (A): Black or bluish lesions: It results from tissue bleeding and retention of blood pigment. 5 DISCUSSION Atypical endometriosis is a rare entity, which may be associated with an increased malignant potential when compared to endometriosis [13,14]. Histologic criteria for establishing the diagnosis have been described by Czer- nobilsky and Morris as severe epithelial atypism, char- acterized by large hyperchromatic or pale nuclei. Complex atypical endometrial hyperplasia is a histologic diagnosis that falls along a spectrum of endometrial pathology. Women with this diagnosis based on endometrial sampling are frequently found to have endometrial cancer at hysterectomy. 1-5 In a recent study by the Gynecologic Oncology Group, 6 42% of women diagnosed with complex atypical endometrial hyperplasia on office endometrial. Atypical endometriosis is rare and difficult to diagnose. The most common atypical locations are the gastrointestinal tract, urinary tract, lung, umbilicus, inguinal area, breast, and pelvic nerves, as well as abdominal surgical scars. Gastrointestinal lesions are the most common extragenital manifestation, and the diaphragm is the most.

In the present pictorial we show the ultrasonographic appearances of endometriosis in atypical sites. Scar endometriosis may present as a hypoechoic solid nodule with hyperechoic spots while umbilical endometriosis may appear as solid or partially cystic areas with ill-defined margins. In the case of endometriosis of the rectus muscle, ultrasonography usually demonstrates a heterogeneous. Atypical endometrial hyperplasia is a precancerous condition that can develop in the lining of the uterus (called the endometrium). It is an overgrowth of abnormal cells, or it can develop from endometrial hyperplasia, which is an overgrowth of normal cells. Sometimes polyps that grow in the uterus will have atypical endometrial hyperplasia Endometriosis and cancer could have some common genetic and epigenetic causes. K-ras mutations in regions of normal endometriosis, atypical endometriosis, and clear cell carcinoma have been described. Reduced expression of PTEN may be involved in the malignant evolution of endometriosis to endometrioid carcinoma and clear cell carcinoma of the. Complex atypical endometrial hyperplasia. 10 Sep 2010 20:47. Feeling a little lost in terms of where to look for help/guidelines and hoping that someone here might be able to help. I'm 36 years old and was diagnosed with complex atypical endometrial hyperplasia following a hysteroscopy and biopsy last March. Due to my age and desire to retain. Hi there, From my recent laparoscopy, the surgeon concluded I have atypical endometriosis. She found a lot of extremely red/raw areas that were fairly wide spread (so did excision at the same time) and apparantly this is how atypical endo often presents itself

Atypical endometriosis: a clinicopathologic study of 163

  1. A high frequency of MSI was found in endometriosis (82.6%) and atypical endometriosis (75%); however, the differences were not significant. These results suggest that LOH at D105608 may possibly be an important molecular event in the progression of endometriosis to carcinoma. This study highlights that endometriosis and atypical endometriosis.
  2. Endometriosis, atypical endometriosis, adjacent endometriosis to clear cell ovarian carcinoma, adjacent endometriosis to endometrioid ovarian carcinoma, clear cell ovarian carcinoma, endometrioid ovarian carcinoma. Contributor(s) Shin HY, Kim JH, Yang WK, Chay DB: Citation(s) 33331115: Submission date: Aug 30, 2020: Last update date: Apr 01.
  3. - Atypical endometriosis can be seen in this context - Sometimes a continuum is seen consisting of endometriosis, atypical endometriosis, and frank carcinoma . General gynecologist o
  4. Endometriosis Online Support Group (FREE and open to the public) Date and Time: Wednesday, February 24, 2021 @ 3 PM, PST Topic: Atypical Locations of Endometriosis Guest Presenter: Sadikah Behbehani, MD, University of California Riverside School of Medicine. Reproductive Endocrinology and Infertility, Minimally Invasive Gynecologic Surgery, Division of Obstetrics and Gynecology, Assistant.
  5. Atypical endometriosis, especially when involving the ovary, is considered a precursor lesion for both endometrioid and clearcell ovarian cancers and carries up to a 4-fold increased risk of.

In non-atypical, atypical endometriosis and CCC groups there are significant differences on the percentage of ARID1A expression (Kruskal-Walis test p=0.0035). There are significant differences on ARID1Aexpression between non-atypical and atypical endometriosis with EAOC (p=0.001 and p=0.0015) Scar endometriosis is an infrequent type of extra pelvic endometriosis that is rather close together with obstetrical and gynaecological surgeries. Scar endometriosis is reported in only 0.03-0.15% of all cases of endometriosis. We are reporting a case of 39years old female patient presenting with scar endometriosis 10 years after her last lower segment caesarean section Endometriosis is defined as presence of endometrium including glands and stroma at locations other than the uterine cavity. Atypical endometriosis is rarely seen, accounting for 4.38% amongst endometriosis cases and is reported to possess a precancerous potential. We are reporting a case of primigravida with term gestation, taken up fo Understanding the atypical locations of endometriosis is key in the appropriate diagnosis and treatment of women with pelvic pain. While a multidisciplinary approach is often necessary to target all aspects of the disease, the initial evaluation should be performed by a gynecologist trained in detecting the disease wherever it may be located.. non- atypical endometriosis (12 of 14) and 100% of the atypical endometriosis (14 of 14), benign (3 of 3), and borderline (6 of 6) clear-cell adenofibroma components were found to be ARID1A deficient. •In contrast, in the 19 patients with ARID1A-intact carcinomas, all of the adjacent precurso

Atypical Sites of Deeply Infiltrative Endometriosis

A histologic study of ovarian endometriosis with emphasis on hyperplastic and atypical changes. Obstet Gynecol 1979; 53:318. Ogawa S, Kaku T, Amada S, et al. Ovarian endometriosis associated with ovarian carcinoma: a clinicopathological and immunohistochemical study This is a recording of the Riverside Medical Clinic Charitable Foundations Endometriosis Online Support Group. Virtual meetings are FREE and participants are.. A 41‐year‐old woman presented with a recurrent endometriosis in a CS scar. Within 16 years it changed from benign to atypical endometriosis and finally to carcinosarcoma after three operations. Complete excision of the tumor was performed, with a big defect of abdominal wall successfully repaired by autologous pedicle skin-muscle graft

Atypical Endometriosis & Malignant Transformation

  1. The common sites of endometriosis are the ovaries, fallopian tubes, pelvic peritoneum, D.P, uterovesical pouch and uterosacral ligaments (alternatively called the pelvic site), whereas the atypical sites of endometriosis include the gastrointestinal tract, urinary tract, soft tissues, and chest (alternatively called the extra-pelvic
  2. It is noteworthy that prior studies have shown a higher frequency of atypia in endometriosis when a co-existent clear cell CA is present. 17,42,50,70 Atypical endometriosis also exhibits a Ki-67 proliferation index intermediate between typical endometriosis and clear cell CA. 72 A large number of molecular and chromosomal alterations have been.
  3. Atypical endometriosis has been proposed as a premalignant lesion strongly associated with endometriosis-associated ovarian cancer (EAOC) [4,5]. Atypical endometriosis also refers to two different histologic findings: cellular atypia, also known as cytologic atypia, and architectural atypia, commonly referred to as hyperplasia
  4. Endometriosis is a common, chronic gynecological condition defined as the presence of functional endometrial glands and stroma-like lesions outside the uterus. It manifests in three ways; superficial (peritoneal) disease, ovarian disease (endometriomas), and deep infiltrating endometriosis, which is the most complex and surgically challenging form..
The characteristic ultrasound features of specific types

Endometrial Hyperplasia: Causes, Symptoms & Treatmen

Pathology Outlines - Endometriosi

Presentation1

Endometriosis‐related pathology: a discussion of selected

suggested that atypical endometriosis is a precursor lesion of endometriosis-associated ovarian cancer (EAOC). The aim of this study is to evaluate if cytologic (cellular) atypia and architectural atypia (hyperplasia), histologic findings described as atypical endometriosis, play a different role in patients with EAOC One of the most intriguing aspects of our case was the association of this neoplasm with foci of ovarian endometriosis and with atypical endometrial hyperplasia (AEH). It is well-known that most of endometrioid and clear cell carcinomas of the ovary arise in association with ovarian endometriosis [ 17 ] The findings of Pearce and collaborators1 regarding the association between endometriosis and ovarian cancer have pathogenic and clinical implications. A relation between endometriosis and low-grade serous invasive ovarian cancer was reported for the first time, in addition to confirmation of the well known association with clear-cell and endometrioid histotypes lymph node endometriosis and atypical ovarian endometriosis including description of a perineural invasion Jiri Lenza,b,c, Radek Chvatald, Ludek Fialae,f, Petra Konecnac, David Lenzb Aim. Endometriosis is an inflammatory condition that shares a number of similarities with malignant diseases, such a

Ovarian atypical endometriosis: its close association with

Introduction. The incidence of endometriosis affecting skin tissue represents only 0.5-1.0% of all endometriosis cases. A malignancy in the abdominal wall arising from endometriosis following cesarean section is even rarer; only 21 cases have previously been reported. The therapeutic strategy has not been determined because of the limited cases management of patients with endometriosis usually followed at our institution. RESULTS At laparoscopy, the mean ASRM score in the group of 47 patients with minimal or mild endometriosis was 2.7 6 1.8 740 Muzii et al. Typical and atypical endometriosis Vol. 74, No. 4, October 200 Atypical Locations of Endometriosis Sadikah Behbehani, MD Minimally Invasive Gynecologic Surgery Reproductive Endocrinology and Infertility . Endometriosis Endometrial glands and stroma outside the uterus •Ovaries, peritoneum, diaphragm, bowel, bladder Symptoms •PAI Atypical Endometriosis: Its Presentation and Management. Authors; Authors and affiliations; Richard E. Blackwell; Chapter. 109 Downloads; Abstract. Jean Miro's painting, head of a woman, accurately describes the dilemma patients and physicians face when dealing with endometriosis. The painting depicts a demon leaping from an abstract head; at. An Atypical Presentation of A Case of Endometriosis N Yusuf1, M A Haque2, M H Rahman3, M A Ali4 Abstract Bloody pleural effusion may be a clinical complication of many diseases like malignancy, trauma, pulmonary infarction, ovarian pathology, certain infections etc. Rarely pulmonary

Key Words: Endometriosis, clear lesions, laparoscopy For patients with chronic pelvic pain, a definitive laparoscopic diagnosis can be made by visual inspec- tion and identification of endometriosis or by ob- taining biopsies of tissue that reveal endometriosis. Atypical (clear, grainy, red, and flame) lesions of en Atypical endometriosis is reported to possess a precancerous potential attributed to premalignant changes characterized by cytological atypia and architecture proliferation. Moreover, the coexistence of atypical endometriosis and neoplasms had been reported. However, cases of atypical endometriosis transformation to carcinoma are rarely reported

Results: Laparoscopically, 469 patients (18.8%) were diagnosed to be endometriosis. Of those, typical and atypical endometriosis were diagnosed in 220 patients (8.8%) and 249 patients (9.98%. The atypical endometriosis has a close association with ovarian epithelial malignancies . Ogawa et al reported that endometriosis associated with ovarian malignancies was typical endometriosis in 35 cases and atypical endometriosis in 29 cases. In the present 6 cases, all the 6 cases were of atypical endometriosis, suggesting that atypical. The carcinoma and contiguous atypical endometriosis show nucleotide variation corresponding to G6139T (as indicated with the dashed box); the tumor shows a heterozygous peak at that location. Rare ( 200 cases reported) Mean age 55 years, range 28-86 years 97% present with stage I disease 36% associated with endometriosis Typically no recurrent disease or metastasis on follow-up, even if intraepithelial carcinoma or microinvasion (Am J Surg Pathol 2003;27:1253, Am J Surg Pathol 2000;24:1465 Endometriosis in the canal of Nuck: atypical manifestations in an unusual location. AJR Am J Roentgenol 2005;185(1): 284-285. Crossref, Medline, Google Scholar; 81 Kirkpatrick A, Reed CM, Bui-Mansfield LT, Russell MJ, Whitford W. Radiologic-pathologic conference of Brooke Army Medical Center: endometriosis of the canal of Nuck

Endometrial hyperplasia ultrasound - wikidoc

7 Self-Care Tips for Women Who Have Endometriosis. Take these steps to put yourself first and prevent symptoms like pelvic pain and cramping from getting in the way of your day-to-day life A type of unusual endometriotic growth called atypical endometriosis may also constitute a precancerous state and is associated with an increased risk of developing endometriosis-associated ovarian cancer. Therefore, be sure to ask your doctor whether any of your endometriosis biopsies came back as atypical Endometriosis, a gynecologic pathology, is defined by the presence of a tissue similar to uterine endometrium, which is located in places other than physiologically appropriate. These endometrial heterotopic islets contain glands and stroma and are functionally capable of responding to exogenous, endogenous, or local hormonal stimuli

Atypical endometriosis and ovarian endometriosis-associated tumors have common molecular damages, such as mutations of PTEN, ARID1A, and hepatocyte nuclear factor-1β (HNF-1β) upregulation. Moreover, mutations of ARID1A were noted in clear cell tumors and atypical endometriosis, but not in the remote endometrioid foci This is a rather atypical case of endometriosis with a large mass infiltrating the uterus (cervix and isthmus) and rectosigmoid colon. There is no evidence of bleeding within the expansion, which is a typical sign of endometrioma. However, there is fibrosis with retraction effect. Glandular appearance is also very rare in endometriosis Abnormal Pap Smears And HPV Abnormal Pap Smears are typically caused by strains of the Human Papilloma Virus, HPV. An abnormal pap smear result does not mean you have cervical cancer. High risk strains can cause more serious cellular changes. Typically, both high and low risk strains of HPV go away within 24 months. It's [

An endometrioma, also called ovarian endometrioma or endometrioid cyst, is a type of cyst formed when endometrial tissue grows in the ovaries. These cysts are benign and estrogen-dependent. An endometrioma which is filled with old blood is called a chocolate cyst. While they sound scary, chocolate cysts are actually common, and benign Classification of Endometriosis. Endometriosis is known to have typical and atypical presentations and may be present superficially over the peritoneum or infiltrate deep into the abdomino-pelvic organs leading to a complete distortion of the anatomy. The need to correctly classify endometriosis is paramount.The ideal classification system for. To assess the risk of endometrial cancer (EC) associated with atypical glandular cells of endometrial origin (AGC-EM) in 2 age groups (age younger than 51 vs 51 years or older). Methods . A retrospective case series was assembled identifying AGC from a pathology database between January 1, 2005 and January 1, 2009 Atypical endometriosis was more common in CA(AF-)s than in AFs, APTs, and CC(AF+)s [p=0.004]. The subset of CA(AF-)s without endometriosis presented more frequently in advanced stage (>I) and were higher grade compared to CA(AF+)s or CA(AF-) with endometriosis (p-values, <0.0001 to 0.0071). All AFs and APTs were stage I compared t

Endometrial CarcinomaPeritoneum | Basicmedical KeyPathology Outlines - Mucinous borderline tumor / atypicalA chest X-ray shows right atrial enlargement

Ovarian atypical endometriosis Ovarian atypical endometriosis Seidman, 1998-02-01 00:00:00 Sir : I read with great interest the study on atypical endometriosis by Fukunaga et al . . I completely agree with their assertion that the frequency of atypical endometriosis in my study was very high due to the referral nature of the AFIP material Patterns of loss of heterozygosity at 10q23.3 and microsatellite instability in endometriosis, atypical endometriosis, and ovarian carcinoma arising in association with endometriosis Rouba Ali-Fehmi, Ibrahim Khalifeh, Sudeshna Bandyopadhyay, W. Dwayne Lawrence, Elvio Silva, Dezhong Liao, Fazlul H. Sarkar, Adnan R. Munkara Atypical stromal cells with severely atypical nuclei exhi-biting multilobulation (A) and multinucleation (B) in the stroma of an endometrial (A) and vaginal (B) polyps. A mast cell (arrowhead) can be noted in the immediate vicinity. Table 1 'LIIHUHQWLDO GLDJQRVHV RI DW\SLFDO VWURPDO FHOOV LQ VSHFL¿